Publications

2007 to date

  • Protein/ice interaction: high-resolution synchrotron X-ray diffraction differentiates pharmaceutical proteins from lysozyme. Bhatnagar, B.; Zakharov, B.; Fisyuk, A.; Wen, X.; Karim, F.; Lee, K.; Seryotkin, Y.; Mogodi, M.; Fitch, A.; Boldyreva, E.; Kostyuchenko, A.; Shalaev, E. J. Phys. Chem. B 2019, 123, 5690-5699.
  • A beetle antifreeze protein protects lactate dehydrogenase under freeze-thawing, Rodriguez, C; Sajjadi, S.; Abrol, R.; Wen, X. Int. J. Biol. Macromol. 2019, 136, 1153-1160.
  • Antifreeze proteins govern the precipitation of trehalose in a freezing-avoiding insect at low temperature. Wen, X.; Wang, S.; Duman, J.G.; Arifin, J.F.; Juwita, V.; Goddard III, W.A.; Rios, A.; Liu, F.; Kim, S.K.; Abrol, R.; DeVries, A.L.; Henling, L.M. Proc. Natl. Acad. Sci. U.S.A. 2016, 113, 6683-6688.
  • Molecular Recognition of Methyl α‑D‑Mannopyranoside by Antifreeze (Glyco)Proteins. Wang, S.; Wen, X.; DeVries, A.L.; Bagdagulyan, Y.; Morita, A.; Golen, J.A.; Duman, J.G.; Rheingold, A.L. J. Am. Chem. Soc. 2014, 136, 8973-8981.
  • Antifreeze Protein-Induced Selective Crystallization of a New Thermodynamically and Kinetically Less Preferred Molecular Crystal. Wang, S.; Wen, X.; Golen, J.A.; Arifin, J.F.; Rheingold, A.L. Chem. Eur. J. 2013, 19, 16104-16112.
  • Thermodynamic analysis of thermal hysteresis: Mechanistic insights into biological antifreezes Wang, S.; Amornwittawat, N.; Wen, X. J. Chem. Thermodynamics 2012, 53, 125-130.
  • Expanding the molecular recognition repertoire of antifreeze polypeptides: effects on nucleoside crystal growth. Wang, S.; Wen, X.; Nikolovski, P.; Juwita, V.; Arifin, J.F. Chem. Commun. 2012, 48, 11555-11557
  • Interaction of reduced nicotinamide adenine dinucleotide with an antifreeze protein from Dendroides canadensis: mechanistic implication of antifreeze activity enhancement. Wen, X.; Wang, S.; Amornwittawat, N.; Houghton, E.A.; Sacco, M.A. J. Mol. Recognit., 2011, 24, 1025-1032.
  • NMR and DFT Investigation of Heme Ruffling: Functional Implications for Cytochrome c. Liptak, M.D.; Wen, X.; Bren, K. L. J. Am. Chem. Soc., 2010, 132, 9753-9763.
  • Arginine, a key residue for the enhancing ability of an antifreeze protein of the beetle Dendroides canadensis. Wang, S.; Amornwittawat, N.; Juwita, V.; Kao, Y.; Duman, J.; Pascal, T.; Goddard, W.; Wen, X. Biochemistry 2009, 48, 9696-9703.
  • Hofmeister Effects of Common Monovalent Salts on the Beetle Antifreeze Protein Activity. Wang, S.; Amornwittawat, N.; Banatlao, J.; Chung, M.; Kao, Y.; Wen, X. J. Phys. Chem. B, 2009, 113, 13891-13894.
  • Effects of Polyhydroxy Compounds on Beetle Antifreeze Protein Activity. Amornwittawat, N.; Wang, S.; Banatlao, J; Chung, M.; Duman, J.G.; Wen, X. Biochim. Biophys. Acta 2009, 1794, 341-346.
  • Polycarboxylates Enhance Beetle Antifreeze Protein Activity. Amornwittawat, N.; Wang, S.; Duman, J.G.; Wen, X. Biochim Biophys Acta, 2008, 1784, 1942-1948.
  • Effects of Heme Pocket Structure and Mobility on Cytochrome c. Wen, X.; Patel, K; Russell, B. S.; Bren, K. L. Biochemistry 2007, 46, 2537-2544.

2006 and earlier

  • Heme Axial Methionine Fluxion in Pseudomonas aeruginosa Asn64Gln Cytochrome c551. Wen, X.; Bren, K. L.Inorg. Chem. 2005, 44, 8587-8593. 
  • Suppression of Axial Methionine Fluxion in Hydrogenobacter thermophilus Gln64Asn Cytochrome c552. Wen, X.; Bren, K. L. Biochemistry 2005, 44, 5225-5233.
  • The Influence of Aqueous vs. Glassy Solvents on Protein Dynamics: Vibrational Echo Experiments and Molecular Dynamics Simulations. Massari, A. M.; Finkelstein, I. J.; McClain, B. L.; Goj, A.; Wen, X.; Bren, K. L.; Loring, R. F.; Fayer, M. D. J. Am. Chem. Soc. 2005, 127, 14279-14289. 
  • The Redox Properties of Wild-type and Heme-binding Loop Mutants of Bacterial Cytochromes c Measured by Direct Electrochemistry. Ye, T.; Kaur, R.; Wen, X.; Bren, K. L.; Elliotta, S. J. Inorg. Chem. 2005, 44, 8999-9006.
  • Folding, Conformational Changes, and Dynamics of Cytochromes c Probed by NMR Spectroscopy. Bren, K. L.; Kellogg, J. A.; Kaur, R.; Wen, X. Inorg. Chem. 2004, 43, 7934-7944.
  • Heme Axial Methionine Fluxionality in Hydrogenobacter thermophilus Cytochrome c552. Zhong, L; Wen, X.; Rabinowitz, T. M.; Russell, B. S.; Karan, E. F.; Bren, K. L. Proc. Natl. Acad. Sci.U.S.A. 2004, 101, 8637-8642.