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NEWS
Samuel received outstanding poster award at the SoCal Undergraduate Research Symposium!
08/08/2023 - Samuel Groysman presented his project titled "Using Mesoporous Silica Films to Enhance Plasmonic Electrochemical Microscopy Signals" at the SoCal Undergraduate Research Symposium. He received one of the Outstanding Poster Awards!
Congratulations 2023 Graduates!
05/28/2023 - Congratulations to Aimee Anguiano, M.S. in Criminalistics, Jennifer Galvez, M.S. in Chemistry, Christina Dhoj, M.S. in Biology, and Sheehan Belleca, B.S. in Biochemistry, for graduating with the Class of 2023. We are thankful for your contributions to our lab, and we are so proud of you!
Welcome our UCI collaborators Prof. Shane Ardo and Nate Keyes!
05/12/2023 - We were delighted to host our esteemed NSF CCI collaborators, Prof. Shane Ardo and Nate Keyes, on May 12th!
OUR RESEARCH
Single cell analysis in Parkinson's disease
Parkinson's disease (PD) is a neurodegenerative disorder characterized by the death of dopamine-producing neurons in the substantia nigra region of the midbrain. In our lab, we study the molecular mechanisms of alpha-synuclein and its aggregates associated with PD using imaging techniques such as scanning ion conductance microscopy and surface plasmon resonance microscopy.
Electrochemistry at nanoscopic interfaces
We are interested in fundamental studies and sensing applications of electrochemistry at nanoscopic interfaces. One project focuses on carbon nanoelectrodes and their applications in intracellular detection of active species and chemical sensing. The second one focuses on understanding interfacial-ion-transfer (IIT) kinetics at nanopipette-supported interface between two immiscible electrolyte solutions (ITIES).
Environmental Applications
We are interested in applying analytical techniques in studying general environmental concerns such as particulate matter (PM) and microplastic pollution. Ongoing projects include (1) monitoring the effect of PM exposure on membranes of human lung cells and neuroblastoma cells using scanning ion conductance microscopy; (2) sampling and characterizing microplastics from LA coastal area; (3) monitoring the degradation of polyethylene terephthalate powder and its effect on adsorbing toxic organic compounds.
Single nanoparticle electrochemistry
Single-Entity Electrochemistry is essential for understanding the fundamental dynamics of real-world systems that are often heterogeneous. We use plasmonic electrochemical microscopy, an optical imaging based electrochemical technique, to study SEE at individual metallic and non-metallic nanoparticles.