Dr. Yixian Wang

College of Natural and Social Sciences
Department of Chemistry & Biochemistry
Office Location ASCB122D
Associate Professor
Research Interests: 
Analytical Chemistry, Nanoscale electrochemistry, Scanning probe microscopy, Plasmonic based imaging and sensing techniques, Single entity analysis, Parkinson's Disease, Environmental Sciences 
CHEM 3500 Quantitative Analysis 
CHEM 4510 Advanced Analytical Chemistry: Optical Spectroscopy
CHEM 4520 Advanced Analytical Chemistry: Analytical Separations and Mass Spectrometry
CHEM 4530 Advanced Analytical Chemistry: Electrochemistry and Surface Techniques  
CHEM 5000 Interdisciplinary Discoveries in Chemistry and Biochemistry
Educational Background:
Postdoctoral Research Associate, Biodesign Institute, Arizona State University, 2013-2016
Ph.D. in Chemistry, The City University of New York, New York, NY, 2007-2013
B. S. in Materials Chemistry, Peking University, Beijing, China, 2002-2006
Selected Publications:
(Please see Google Scholar Citation for a full list of publications, student authors from CSULA are highlighted in bold)
  • B. A. Beadell, A. Chieng, K. R Parducho, Z. Dai, S. Ho, G. Fujii, Y. Wang, E. Porter* "Nano- and Macroscale Imaging of Cholesterol Linoleate and Human Beta Defensin 2-Induced Changes in Pseudomonas aeruginosa Biofilms" Antibiotics2021, 10 (11), 1279  
  • A. GarciaK. Wang, F. Bedier, M. Benavides, Z. Wang, S. Wang, Y. Wang* "Plasmonic Imaging of Electrochemical Reactions at Individual Prussian Blue Nanoparticles" Front. Chem., 2021, 9, 718666   
  • A. Garcia, S. Wang, N. Tao, X. Shan*, Y. Wang* "Plasmonic Imaging of Oxidation and Reduction of Single Gold Nanoparticles and Their Surface Structural Dynamics" ACS Sens. 2020, 6 (2), 502-507
  • J. Parres-Gold, A. Chieng, S. Wong Su,  Y. Wang* “Real-Time Characterization of Cell Membrane Disruption by α-Synuclein Oligomers in Live SH-SY5Y Neuroblastoma Cells” ACS Chem. Neurosci.2020, 11 (17), 2528-2534
  • K. R Parducho, B. Beadell, T. Ybarra, M. Bush, E. Escalera, A. T. Trejos, A. Chieng, M. Mendez, C. Anderson, H. Park, Y. Wang, W. Lu, E. Porter* “The Antimicrobial Peptide Human Beta-Defensin 2 Inhibits Biofilm Production of Pseudomonas aeruginosa Without Compromising Metabolic Activity” Front Immunol, 2020, 11, 805
  • M. Chang, G. Morgan, F. Bedier, A. Chieng, P. Gomez, S. Raminani, Y. Wang* “Recent advances in nanosensors built with pre-pulled glass nanopipettes and their applications in chemical and biological sensing” J. Electrochem. Soc., 2020, 167 (3), 037533
  • Q. Liu, X. Wang*, A. Benedict, L. Janibekyan, S. Wong Su, Y. Wang*, F. Zhou* “Surface Plasmon Resonance Coupled with Potential-Step Chronoamperometry: Theory and Applications for Quantitative Measurements of Electrodeposited Thin Films”. Electroanalysis, 2019, 31, 1-8.
  • A. Chieng, M. Chiang, K. Triloges, M. Chang and Y. Wang* “Recent progress in the studies of electrochemical interfaces by surface plasmon resonance spectroscopy and microscopy”, Curr. Opin. Electrochem. 2019, 13, 94.
  • S. Wong Su, A. Chieng, J. Parres-Gold, M. Chang, Y. Wang* “Real-time determination of aggregated alpha-synuclein induced membrane disruption at neuroblastoma cells using scanning ion conductance microscopy” Faraday Discuss., 2018, 210, 131
  • Y. Wang, D. Wang, M. V. Mirkin “Resistive-pulse and Rectification Sensing with Glass and Carbon Nanopipettes” invited article for Proc. R. Soc. A, 2017, 473, 20160931
  • Y. Wang, X. Shan, S. Wang, N. Tao “Plasmonic Imaging of Surface Electrochemistry of Single Gold Nanowires”, J. Am. Chem. Soc., 2017, 139, 1376
  • Y. Wang, X. Shan, N. Tao “Emerging Tools for Studying Single Entity Electrochemistry”, Faraday Discuss, 2016, 193, 9
  • Y. Wang, X. Shan, S. Wang, N. Tao, P. Y. Blanchard, Y. Yu, K. Hu, and M. V. Mirkin “Imaging Local Electric Field Distribution by Plasmonic Impedance Microscopy” Anal. Chem. 2016, 88, 1547
  • Y. Wang, X. Shan, F. Cui, J. Li, S. Wang, N. Tao, “Electrochemical Reactions in Sub-femtoliter-Droplets Studied with Plasmonics-based Electrochemical Current Microscopy” Anal. Chem. 2014, 87, 494
  • Y. Wang, K. Kececi, M. V. Mirkin “Electron Transfer/Ion Transfer Mode of the Scanning Electrochemical Microscope (SECM)”, Chem. Sci., 2013 ,4, 3606
  • Y. Wang, K. Kececi, M. V. Mirkin, V. Mani, N. Sardesai and J. F. Rusling “Resistive-Pulse Measurements with Nanopipettes: Detection of Au Nanoparticles and Nanoparticle-Bound Anti-peanut IgY”, Chem. Sci., 2013 ,4, 655
  • Y. Wang, J.-M. Noel, J. Velmurugan, W. Nogala, M. V. Mirkin, С. Lu, M. G. Collignonl, F. Lemaître and C. Amatore “Nanoelectrodes for Determination of Reactive Oxygen and Nitrogen Species inside Biological Cells” Proc. Nat. Acad. Sci., 2012, 109, 11534.
  • Y. Wang, T. Kakiuchi, F. Shigematsu and M. V. Mirkin “Kinetics of Ion Transfer at the Ionic Liquid/Water NanointerfaceJ. Am. Chem. Soc., 2010, 132, 16945.
  • Y. Wang, J. Velmurugan and M. V. Mirkin, P. J. Rodgers, J. Kim and S.Amemiya “Kinetic Study of Rapid Transfer of Tetraethylammonium at the 1,2-Dichloroethane/Water Interface by Nanopipet Voltammetry of Common IonsAnal. Chem., 2010, 82, 77.
NSF CAREER (PI, 2021-2026)
NIH Research Enhancement Award (R15, PI, 2020-2023)
NSF-Major Research Instrumentation (PI, 2018-2021)
NSF CREST (Co-PI, 2022-2027)
La Kretz Environment Endowment (PI, 2018-2019)
NSF-PREM (seed grant PI, 2018-2019
CSUPERB New Investigator Grant (PI, 2017-2019)