The editing mechanism involves a bifunctional domain called the DYW deaminase. The DYW domain binds zinc ions and has structural features common to cytidine deaminases. We are investigating the biochemical mechanisms governing its activity.
The editing mechanism involves a bifunctional domain called the DYW deaminase. The DYW domain binds zinc ions and has structural features common to cytidine deaminases. We are investigating the biochemical mechanisms governing its activity.