# #BLOSUM35 amino acid substitution matrix # #February 20, 1996 14:54 # A B C D E F G H I K L M N P Q R S T V W X Y Z * A 5 -1 -2 -1 -1 -2 0 -2 -1 0 -2 0 -1 -2 0 -1 1 0 0 -2 0 -1 -1 -5 B -1 5 -2 5 0 -2 0 0 -2 0 -2 -2 4 -1 0 -1 0 -1 -2 -3 -1 -2 0 -5 C -2 -2 15 -3 -1 -4 -3 -4 -4 -2 -2 -4 -1 -4 -3 -3 -3 -1 -2 -5 -2 -5 -2 -5 D -1 5 -3 8 2 -3 -2 0 -3 -1 -2 -3 1 -1 -1 -1 -1 -1 -2 -3 -1 -2 1 -5 E -1 0 -1 2 6 -3 -2 -1 -3 1 -1 -2 -1 0 2 -1 0 -1 -2 -1 -1 -1 5 -5 F -2 -2 -4 -3 -3 8 -3 -3 1 -1 2 0 -1 -4 -4 -1 -1 -1 1 1 -1 3 -3 -5 G 0 0 -3 -2 -2 -3 7 -2 -3 -1 -3 -1 1 -2 -2 -2 1 -2 -3 -1 -1 -2 -2 -5 H -2 0 -4 0 -1 -3 -2 12 -3 -2 -2 1 1 -1 -1 -1 -1 -2 -4 -4 -1 0 -1 -5 I -1 -2 -4 -3 -3 1 -3 -3 5 -2 2 1 -1 -1 -2 -3 -2 -1 4 -1 0 0 -3 -5 K 0 0 -2 -1 1 -1 -1 -2 -2 5 -2 0 0 0 0 2 0 0 -2 0 0 -1 1 -5 L -2 -2 -2 -2 -1 2 -3 -2 2 -2 5 3 -2 -3 -2 -2 -2 0 2 0 0 0 -2 -5 M 0 -2 -4 -3 -2 0 -1 1 1 0 3 6 -1 -3 -1 0 -1 0 1 1 0 0 -2 -5 N -1 4 -1 1 -1 -1 1 1 -1 0 -2 -1 7 -2 1 -1 0 0 -2 -2 0 -2 0 -5 P -2 -1 -4 -1 0 -4 -2 -1 -1 0 -3 -3 -2 10 0 -2 -2 0 -3 -4 -1 -3 0 -5 Q 0 0 -3 -1 2 -4 -2 -1 -2 0 -2 -1 1 0 7 2 0 0 -3 -1 -1 0 4 -5 R -1 -1 -3 -1 -1 -1 -2 -1 -3 2 -2 0 -1 -2 2 8 -1 -2 -1 0 -1 0 0 -5 S 1 0 -3 -1 0 -1 1 -1 -2 0 -2 -1 0 -2 0 -1 4 2 -1 -2 0 -1 0 -5 T 0 -1 -1 -1 -1 -1 -2 -2 -1 0 0 0 0 0 0 -2 2 5 1 -2 0 -2 -1 -5 V 0 -2 -2 -2 -2 1 -3 -4 4 -2 2 1 -2 -3 -3 -1 -1 1 5 -2 0 0 -2 -5 W -2 -3 -5 -3 -1 1 -1 -4 -1 0 0 1 -2 -4 -1 0 -2 -2 -2 16 -1 3 -1 -5 X 0 -1 -2 -1 -1 -1 -1 -1 0 0 0 0 0 -1 -1 -1 0 0 0 -1 -1 -1 0 -5 Y -1 -2 -5 -2 -1 3 -2 0 0 -1 0 0 -2 -3 0 0 -1 -2 0 3 -1 8 -1 -5 Z -1 0 -2 1 5 -3 -2 -1 -3 1 -2 -2 0 0 4 0 0 -1 -2 -1 0 -1 4 -5 * -5 -5 -5 -5 -5 -5 -5 -5 -5 -5 -5 -5 -5 -5 -5 -5 -5 -5 -5 -5 -5 -5 -5 1