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1. Create your own scoring matrix for protein sequence comparisons.
For example, the matrix may be designed to penalize hydrophobic amino acids. It
is advisable to use one of the pre-existing BLOSUM
or PAM matrices as a template to build your matrix. Show that your scoring matrix gives a
logical dotter output
for protein sequences of your choice. Print a hard copy of your scoring matrix,
your protein sequences and the dotter output using your scoring matrix. Explain
the rationale for the scoring matrix that you create. |