Representative Publications

Meng, J., G. Kanzaki, D. Meas, C. K. Lam, H. Crummer, J. Tain and H. H. Xu. 2012. A genome-wide inducible phenotypic screen identifies antisense RNA constructs silencing Escherichia coli essential genes. FEMS Microbiol Lett. 329(1):45-53.

Yuan, H., S. C. Chai, C. K. Lam, H. H. Xu and Q. Z. Ye. 2011. Two methionine aminopeptidases from Acinetobacter baumannii are functional enzymes. Bioorg Med Chem Lett. 21(11):3395-8.

Golanbar, G. D., C. K. Lam, Y. M. Chu, C. Cueva, S. W. Tan, I. Silva and H. H. Xu. 2011. Phenotypic and molecular characterization of Acinetobacter clinical isolates obtained from inmates of California correctional facilities. Journal of Clinical Microbiology. 49(6):2121-31.

Xu, H. H., J. D. Trawick, R. J. Haselbeck, R. A. Forsyth, R. T. Yamamoto, R. Archer, J. Patterson, M. Allen, J. M. Froelich, I. Taylor, D. Nakaji, R. Maile, K. G C, M. Pilcher, V. Brown-Driver, M. McCarthy, A. Files, D. Robbins, P. King, S. Sillaots, C. Malone, C. S. Zamudio, T. Roemer, L. Wang, P. J. Youngman, D. Wall. 2010. Staphylococcus aureus TargetArray: Comprehensive differential essential gene expression as a mechanistic tool to profile antibacterials. Antimicrob Agents Chemother. 2010. 54:3659-3670.

Peng, Y., C. Wang, H. H. Xu, Y. N. Liu and F. Zhou. 2010. Binding of -synuclein with Fe³⁺ and with Fe²⁺ and biological implications of the resultant complexes. Journal of Inorganic Biochemistry. Journal of Inorganic Biochemistry. 104: 365-370.

Xu, H. H. 2010. Assay development for antimicrobial drug discovery. in T. Chen (ed.) A Practical Guide to Assay Development and High-Throughput Screening in Drug Discovery. Taylor and Francis; Boca Raton.

Piyasena, M. E., L. J. Real, R. A. Diamond, H. H. Xu and F. A. Gomez. 2008. Magnetic microsphere-based methods to study the interaction of teicoplanin with peptides and bacteria. Analytical and Bioanalytical Chemistry. 392: 877-886.

Valentine, S. C., D. Contreras, S. Tan, L. J. Real, S. Chu and H. H. Xu. 2008. Phenotypic and molecular characterization of Acinetobacter baumannii clinical isolates from nosocomical outbreaks in Los Angeles County, California. Journal of Clinical Microbiology. 46: 2499-2507.

Xu, H. H., L. Real, and M. W. Bailey. 2006. An array of Escherichia coli clones over-expressing essential proteins: an new strategy of identifying cellular targets of potent antibacterial compounds. Biochemical and Biophysical Research Communications. 349 (4): 1250-1257.

Forsyth, R. A., R. J. Haselbeck, K. L. Ohlsen, R. T. Yamamoto, H. Xu, J. D. Trawick, D. Wall, L. Wang, V. Brown-Driver, J. M. Froelich, G. C. Kedar, P. King, M. McCarthy, C. Malone, B. Misiner, D. Robbins, Z. Tan, Z, Zhu, G. Carr, D. A. Mosca, C. Zamudio, J. G. Foulkes, and J. W. Zyskind. 2002. A genome-wide strategy for the identification of essential genes in Staphylococcus aureus. Molecular Microbiology. 43:1387-1400.

Xu, H. H. 1998. ATP-TOX system - a review. pp153-159. in P. G. Wells, K. Lee and C. Blaise (eds.) Microscale Aquatic Toxicology - Advances, Techniques and Practice. CRC Lewis Publishers, Boca Raton, Florida.

Xu, H. H. and F. R. Tabita. 1996. Ribulose bisphosphate carboxylase/oxygenase gene expression and diversity in Lake Erie planktonic microorganisms. Applied and Environmental Microbiology. 62: 1913-1921.

Gibson, J. L., Y. Qian, G. C. Paoli, J. M. Dubbs, H. H. Xu, H. V. Modak, K. M. Horken, T. M. Wahlund, G. M. F. Watson and F. R. Tabita. 1996. Molecular control and biochemistry of CO₂ fixation in photosynthetic bacteria. in M. E. Lidstrom and F. R. Tabita (eds.) The Proceedings of 8th International C1 Symposium. Kluwer Academic Publishers, The Netherlands.

Xu, H. H., J. Janka, M. Viebahn and R. S. Hanson. 1995. Nucleotide sequence of mxcQ and mxcE genes, required for methanol dehydrogenase synthesis in Methylobacterium organophilum strain XX: a two component regulatory system. Microbiology 141: 2543-2551.

Xu, H. H. and F. R. Tabita. 1994. Positive and negative regulation of sequences upstream of the form II cbb CO2 fixation operon of Rhodobacter sphaeroides. Journal of Bacteriology. 176: 7299-7308.

Xu, H. H., M. Viebahn and R. S. Hanson. 1993. Identification of methanol regulated promoters from Methylobacterium organophilum XX. Journal of General Microbiology. 139: 743-752.

Patents and Patent Applications

Zyskind, J. W., Ohlsen, K.L., Trawick, J.D., Forsyth, R. A., Froelich, J. M., Carr, G. J., Yamamoto, R. T., Xu, H. 2000. Genes identified as required for proliferation in Escherichia coli. US# 6,720,139.

Haselbeck, R., Ohlsen, K. L., Zyskind, J. W., Wall, D., Trawick, J. D., Carr, G. J., Yamamoto, R.T., Xu, H. H. 2001. Genes identified as required for proliferation in bacteria. Publication No. WO 0170955.

Carr, G., Xu, H. H., Foulkes, J. G., Zamudio, C., Haselbeck, R., Ohlsen, K. L., Zyskind, J. W., Wall, D., Trawick, J. D., Yamamoto, R. T., Roemer, T., Jiang, B., Boone, C., Bussey, H. 2001. Methods for identifying the target of a compound which inhibits cellular proliferation. Publication No. WO 02086097.

Wang, L., Zamudio, C., Malone, C., Haselbeck, R., Ohlsen, K. L., Zyskind, J. W., Wall, D., Trawick, J. D., Carr, G. J., Yamamoto, R., Forsyth, R. A., Xu, H. H. 2002. Identification of essential genes in microorganisms.  Publication No. WO 02077183.