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H. Howard Xu, Ph.D.

Phone: (323) 343-2188
 Email: hxu3@calstatela.edu

Representative Publications

Xu, H. H., L. Real, and M. W. Bailey. 2006. An array of Escherichia coli clones over-expressing essential proteins: an new strategy of identifying cellular targets of potent antibacterial compounds. Biochemical and Biophysical Research Communications. 349 (4): 1250-1257.

Forsyth, R. A., R. J. Haselbeck, K. L. Ohlsen, R. T. Yamamoto, H. Xu, J. D. Trawick, D. Wall, L. Wang, V. Brown-Driver, J. M. Froelich, G. C. Kedar, P. King, M. McCarthy, C. Malone, B. Misiner, D. Robbins, Z. Tan, Z, Zhu, G. Carr, D. A. Mosca, C. Zamudio, J. G. Foulkes, and J. W. Zyskind. 2002. A genome-wide strategy for the identification of essential genes in Staphylococcus aureus. Molecular Microbiology. 43:1387-1400.

Xu, H. H. 1998. ATP-TOX system - a review. pp153-159. in P. G. Wells, K. Lee and C. Blaise (eds.) Microscale Aquatic Toxicology - Advances, Techniques and Practice. CRC Lewis Publishers, Boca Raton, Florida.

Xu, H. H. and F. R. Tabita. 1996. Ribulose bisphosphate carboxylase/oxygenase gene expression and diversity in Lake Erie planktonic microorganisms. Applied and Environmental Microbiology. 62: 1913-1921.

Gibson, J. L., Y. Qian, G. C. Paoli, J. M. Dubbs, H. H. Xu, H. V. Modak, K. M. Horken, T. M. Wahlund, G. M. F. Watson and F. R. Tabita. 1996. Molecular control and biochemistry of CO2 fixation in photosynthetic bacteria. in M. E. Lidstrom and F. R. Tabita (eds.) The Proceedings of 8th International C1 Symposium. Kluwer Academic Publishers, The Netherlands.

Xu, H. H., J. Janka, M. Viebahn and R. S. Hanson. 1995. Nucleotide sequence of mxcQ and mxcE genes, required for methanol dehydrogenase synthesis in Methylobacterium organophilum strain XX: a two component regulatory system. Microbiology 141: 2543-2551.

Xu, H. H. and F. R. Tabita. 1994. Positive and negative regulation of sequences upstream of the form II cbb CO2 fixation operon of Rhodobacter sphaeroides. Journal of Bacteriology. 176: 7299-7308.

Xu, H. H., M. Viebahn and R. S. Hanson. 1993. Identification of methanol regulated promoters from Methylobacterium organophilum XX. Journal of General Microbiology. 139: 743-752.

Patents and Patent Applications

Zyskind, J. W., Ohlsen, K.L., Trawick, J.D., Forsyth, R. A., Froelich, J. M., Carr, G. J., Yamamoto, R. T., Xu, H. 2000. Genes identified as required for proliferation in Escherichia coli. US# 6,720,139.

Haselbeck, R., Ohlsen, K. L., Zyskind, J. W., Wall, D., Trawick, J. D., Carr, G. J., Yamamoto, R.T., Xu, H. H. 2001. Genes identified as required for proliferation in bacteria. Publication No. WO 0170955.

Carr, G., Xu, H. H., Foulkes, J. G., Zamudio, C., Haselbeck, R., Ohlsen, K. L., Zyskind, J. W., Wall, D., Trawick, J. D., Yamamoto, R. T., Roemer, T., Jiang, B., Boone, C., Bussey, H. 2001. Methods for identifying the target of a compound which inhibits cellular proliferation. Publication No. WO 02086097.

Wang, L., Zamudio, C., Malone, C., Haselbeck, R., Ohlsen, K. L., Zyskind, J. W., Wall, D., Trawick, J. D., Carr, G. J., Yamamoto, R., Forsyth, R. A., Xu, H. H. 2002. Identification of essential genes in microorganisms.  Publication No. WO 02077183.