College of Natural and Social Sciences

Department of Biological Sciences

Hyunsook Park, PhD                              Office: Biological Sciences 214
 Assistant Professor                                          Phone: (323) 343-2060                                                                  

                                                                                         FAX: (323) 343-6451
                                                                                         email address: hpark8@exchange.calstatela.edu

                                                   Office Hour : Thursday 1:00 - 3:40 PM


BACKGROUND

Dr.Park received her Ph.D. Microbiology from Ewha Women's University (Seoul, Korea)  in 2002, followed by postdoctoral training in mycology and molecular biology at the Division of Infectious Diseases, Harbor-UCLA Medical Center.  Dr. Park joined the Department of Biological Sciences at Cal State LA in 2008.



TEACHING INTERESTS

Dr. Park currently teaches courses in Introductory Biology, General Microbiology, Pathogenic Bacteria, Molecular Genetics and Fungal Pathogenesis. In addition, she provides research training to students in the Dept. of Biological Sciences.


Lecture materials : BIOL416 Molecular Genetics

Lecture materials : MICR454L Special Topics on Microbiology : Fungal pathogenesis



RESEARCH

Dr. Park's research program focuses on host-pathogen interactions in infectious disease.  In particular, she has focused on the pathogenic mechanisms of the fungus, Candida albicans


Date   Recent Publications
2008Gank KD, Yeaman MR, Kojima S, Yount NY, Park H, Edwards, Jr. JE, Filler SG, and Fu Y. SSD1 is Integral to Host Defense Peptide Resistance in Candida albicans. Eukaryot Cell
2008Barker KS, Park H, Phan QT, Xu L, Homayouni R, Rogers PD, Filler SG. Transcriptome Profile of the Vascular Endothelial Cell Response to Candida albicans. J. Infect Dis. 2008 May 23. [Epub ahead of print] (contributed equally)
2008 Goyard S, Knechtle P, Chauvel M, Mallet A, Prévost MC, Proux C, Coppée JY, Schwartz P, Dromer F, Park H, Filler SG, Janbon G, d'Enfert C.  The Yak1 Kinase is Involved in the Initiation and Maintenance of Hyphal Growth in Candida albicans. Mol Biol Cell. 2008 Mar 5 [Epub ahead of print]
2007 Thewes S, Kretschmar M, Park H, Schaller M, Filler SG, Hube B.  In vivo and ex vivo comparative transcriptional profiling of invasive and non-invasive Candida albicans isolates identifies genes associated with tissue invasion.    Mol Microbiol. 2007 Mar;63(6):1606-28.
2006
Martinez-Lopez R, Park H, Myers CL, Gil C, Filler SG. Candida albicans Ecm33p is important for normal cell wall architecture and interactions with host cells. Eukaryot Cell. 2006 Jan;5(1):140-7
2005
Park H, Myers CL, Sheppard DC, Phan QT, Sanchez AA, E Edwards J, Filler SG. Role of the fungal Ras-protein kinase A pathway in governing epithelial cell interactions during oropharyngeal candidiasis. Cell Microbiol. 2005 Apr;7(4):499-510. Links
2003

Choi S, Park N, Park H, Park M, Woo J, Choi W  Interacting domain between yeast chitin synthase 3 and chitin synthase 4 is involved in angiogenesis of chitin ring, but not for cell wall chitin.  J Microbiol Biotechnol 13:263-268  
2002 Park H, Choi S, Park N, Kim C, Kim S, Choi W  Identification of a domain in yeast chitin synthase 3 interacting with chitin synthase 4 by two hybrid analysis.  J Microbiol Biotechnol 12:943-949
2002 Kim M, Park H, C Kim, Park H, Choi W  Inhibition of chitin synthases by nikkomycin is dependent on media composition in Candida albicans.  Yeast 19:341-349.
2001 Min J, Lee Y, Kim Y, Park H, Han S, Jhon G-J, Choi W  Lysophosphatidylcholine derived from deer antler extract suppresses hyphal transition in Candida albicans through MAP kinase activity.  Biochim Biophysica Acta 1531:77-89.
1998 Park H, Jhon G-J, Choi W  Hyphal growth inhibition by deer antler extract mimics the effect of chitin synthase deletion in Candida albicans.  J Microbiol Biotechnol 8:422-425
1998 Park H, John G-J, Choi W  1998 Deer antler extract selectively suppresses hyphal growth in dimorphic fungus, Candida albicans.  J Microbiol Biotechnol 8:291-294


EDUCATIONAL BACKGROUND

Ph.D. Microbiology (emphasis in mycology, molecular biology) 2002
Ewha Women's University, Seoul, Korea
  B.S. Biology (Minor: Science Education) 1996
Ewha Women's University, Seoul, Korea