April 23, 2010
Estimation of the Boundary Conditions for Cryogenic Cooling of Tissues during Laser Therapy
LSAMP VI Bridges to the Doctorate Scholar
Cryogen spray cooling (CSC) is an effective method that reduces skin damage during laser therapy in vascular lesions, such as the removal of port wine stain (PWS) birthmarks and other specific dermatology procedures. The objective of this study is to develop a methodology that can be used to determine the boundary condition, either in temperature or heat extraction that is necessary to model the heat transfer process occurring when cryogenic cooling spray is applied to the surface of the skin prior to laser radiation. Based on a direct approach, the one-dimensional heat conduction model is first solved to find the temperature distribution inside the skin. Later these interior temperature values are used to compute the corresponding heat transfer at the boundary via numerical optimization. In both stages of the solution process, the governing equations are solved by finite-elements-based COMSOL Multiphysics software. The accurate determination of the boundary condition will improve and promote safer laser-based therapeutic procedures.
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