CINQA Seminar Series Fall 2011

Matteo Pellegrini, Ph.D. - Friday, September 23, 2011

Assistant Professor of Department of Molecular, Cell and Developmental Biology
University of California Los Angeles

"Transgenerational Inheritance of DNA Methylation"

DNA Methylation is thought to play an important role in the regulation of gene expression and cellular differentiation.  Recently it has become possible to profile the entire DNA methylome using bisulfite sequencing coupled with next generation sequencers.  Using these approaches several studies have identified regions that are differentially methylated across different cell types.  However, the degree to which DNA methylation responds to environmental cues, is heritable across generations, and affects organismal phenotypes are open questions.  We are currently investigating how patterns of DNA methylation are preserved in parental and F1 crosses in both rice and mice.  We are also investigating the role that diet plays on transgenerational DNA methylation patterns in mice.  Finally we are performing association studies between DNA methylation and clinical phenotypes in mice.  A fuller understanding of these effects will allow us to more completely understand how the effects of environmental changes can be propagated across generations.

Time: 1:00 p.m. in Biological Sciences Room 144.

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Jared Strasburg, Ph.D. - Tuesday, November 22, 2011

Department of Biology
Indiana University

"Genomic evolutionary hybridization and adaptation in annual sunflowers "

Time: 12:10 p.m. in Biological Sciences Room 244.

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Andres Aguilar, Ph.D. - Tuesday, November 29, 2011

School of Natural Sciences
University of California, Merced

"Conserving eolutionary history in an ever changing landscape - the case of California's native freshwater ichthyofauna "

Time: 12:10 p.m. in Biological Sciences Room 244.

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Jennifer Mandel, Ph.D. - Thursday, December 1, 2011

Department of Plant Biology
University of Georgia

"Evolutionary genomics and conservation in sunflowers "

Time: 12:10 p.m. in Biological Sciences Room 244.

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Craig Barrett, Ph.D. - Tuesday, December 6, 2011

Department of Plant Biology
Cornell University

"Genomic evolutionary hybridization and adaptation in annual sunflowers "

Time: 12:10 p.m. in Biological Sciences Room 244.

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